Modification of Fibronectin by Non-Enzymatic Glycation Impairs K(+) Channel Function in Rat Cerebral Artery Smooth Muscle Cells

Fibronectin (FN) enhances K(+) channel activity by integrin-mediated mechanisms. As vascular smooth muscle (VSM) K(+) channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signaling of this extracellular matrix protein thro...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Nourian, Zahra, Li, Min, Sun, Zhe, Zhang, Liping, Davis, Michael J., Meininger, Gerald A., Wu, Jianbo, Braun, Andrew P., Hill, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272009/
https://www.ncbi.nlm.nih.gov/pubmed/35832482
http://dx.doi.org/10.3389/fphys.2022.871968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272009/
https://www.ncbi.nlm.nih.gov/pubmed/35832482
http://dx.doi.org/10.3389/fphys.2022.871968

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