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Modification of Fibronectin by Non-Enzymatic Glycation Impairs K(+) Channel Function in Rat Cerebral Artery Smooth Muscle Cells

Fibronectin (FN) enhances K(+) channel activity by integrin-mediated mechanisms. As vascular smooth muscle (VSM) K(+) channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signaling of this extracellular matrix protein thro...

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Detalles Bibliográficos
Autores principales:	Yang, Yan, Nourian, Zahra, Li, Min, Sun, Zhe, Zhang, Liping, Davis, Michael J., Meininger, Gerald A., Wu, Jianbo, Braun, Andrew P., Hill, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272009/ https://www.ncbi.nlm.nih.gov/pubmed/35832482 http://dx.doi.org/10.3389/fphys.2022.871968

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