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Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits
Causal inference is a critical step in improving our understanding of biological processes, and Mendelian randomization (MR) has emerged as one of the foremost methods to efficiently interrogate diverse hypotheses using large-scale, observational data from biobanks. Although many extensions have bee...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272036/ https://www.ncbi.nlm.nih.gov/pubmed/35832928 http://dx.doi.org/10.1016/j.xhgg.2022.100124 |