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Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits

Causal inference is a critical step in improving our understanding of biological processes, and Mendelian randomization (MR) has emerged as one of the foremost methods to efficiently interrogate diverse hypotheses using large-scale, observational data from biobanks. Although many extensions have bee...

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Detalles Bibliográficos
Autores principales: Sulc, Jonathan, Sjaarda, Jennifer, Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272036/
https://www.ncbi.nlm.nih.gov/pubmed/35832928
http://dx.doi.org/10.1016/j.xhgg.2022.100124