Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease

The prodromal phase of Parkinson’s disease is characterized by aggregation of the misfolded pathogenic protein α-synuclein in select neural centres, co-occurring with non-motor symptoms including sensory and cognitive loss, and emotional disturbances. It is unclear whether neuronal loss is significa...

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Detalles Bibliográficos
Autores principales: Kulkarni, Aishwarya S, Burns, Matthew R, Brundin, Patrik, Wesson, Daniel W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272065/
https://www.ncbi.nlm.nih.gov/pubmed/35822101
http://dx.doi.org/10.1093/braincomms/fcac165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272065/
https://www.ncbi.nlm.nih.gov/pubmed/35822101
http://dx.doi.org/10.1093/braincomms/fcac165

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