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Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease
The prodromal phase of Parkinson’s disease is characterized by aggregation of the misfolded pathogenic protein α-synuclein in select neural centres, co-occurring with non-motor symptoms including sensory and cognitive loss, and emotional disturbances. It is unclear whether neuronal loss is significa...
Autores principales: | Kulkarni, Aishwarya S, Burns, Matthew R, Brundin, Patrik, Wesson, Daniel W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272065/ https://www.ncbi.nlm.nih.gov/pubmed/35822101 http://dx.doi.org/10.1093/braincomms/fcac165 |
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