Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition

Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocytic MAOB has been studied in MAOB null knockout (KO) mice, although MAOB is expressed throughout the body. Therefore, there has been a need for genetically engineered mi...

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Detalles Bibliográficos
Autores principales: Lee, Jung Moo, Sa, Moonsun, An, Heeyoung, Kim, Jong Min Joseph, Kwon, Jea, Yoon, Bo-Eun, Lee, C. Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272118/
https://www.ncbi.nlm.nih.gov/pubmed/35786639
http://dx.doi.org/10.5607/en22016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272118/
https://www.ncbi.nlm.nih.gov/pubmed/35786639
http://dx.doi.org/10.5607/en22016

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