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Hypocretin-1 measurements in cerebrospinal fluid using radioimmunoassay: within and between assay reliability and limit of quantification

STUDY OBJECTIVES: The most sensitive and specific investigative method for the diagnosis of narcolepsy type 1 (NT1) is the determination of hypocretin-1 (orexin-A) deficiency (≤110 pg/mL) in cerebrospinal fluid using a radioimmunoassay (RIA). We aimed to assess the reliability of the Phoenix Pharmac...

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Detalles Bibliográficos
Autores principales: van der Hoeven, Adrienne Elisabeth, van Waaij, Kevin, Bijlenga, Denise, Roelandse, Frederik Willem Cornelis, Overeem, Sebastiaan, Bakker, Jaap Adriaan, Fronczek, Rolf, Lammers, Gert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272241/
https://www.ncbi.nlm.nih.gov/pubmed/35512685
http://dx.doi.org/10.1093/sleep/zsac103