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Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation

The nucleotide context surrounding stop codons significantly affects the efficiency of translation termination. In eukaryotes, various 3′ contexts that are unfavorable for translation termination have been described; however, the exact molecular mechanism that mediates their effects remains unknown....

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Detalles Bibliográficos
Autores principales: Biziaev, Nikita, Sokolova, Elizaveta, Yanvarev, Dmitry V., Toropygin, Ilya Yu, Shuvalov, Alexey, Egorova, Tatiana, Alkalaeva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272376/
https://www.ncbi.nlm.nih.gov/pubmed/35700825
http://dx.doi.org/10.1016/j.jbc.2022.102133