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The Role and Therapeutic Perspectives of Sirtuin 3 in Cancer Metabolism Reprogramming, Metastasis, and Chemoresistance

Sirtuin 3 (SIRT3), the nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase, acts as a metabolic modulator mainly located in mitochondria via regulating the process of the relevant biochemical processes by targeting crucial mediators. Recently, owing to its dual role in cancer, SIRT3 has...

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Detalles Bibliográficos
Autores principales: Zhao, QingYi, Zhou, Jing, Li, Feng, Guo, Sen, Zhang, Liang, Li, Jing, Qi, Qin, Shi, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272524/
https://www.ncbi.nlm.nih.gov/pubmed/35832551
http://dx.doi.org/10.3389/fonc.2022.910963