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Multiplex immunohistochemistry defines the tumor immune microenvironment and immunotherapeutic outcome in CLDN18.2-positive gastric cancer

BACKGROUND: The FAST study identified claudin-18 (CLDN18.2) as a promising novel therapeutic target for gastric cancer (GC). However, the tumor immune microenvironment and clinicopathological features of CLDN18.2-positive GC are unclear, making it difficult to develop and optimize CLDN18.2-targeted...

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Detalles Bibliográficos
Autores principales: Jia, Keren, Chen, Yang, Sun, Yu, Hu, Yajie, Jiao, Lei, Ma, Jie, Yuan, Jiajia, Qi, Changsong, Li, Yanyan, Gong, Jifang, Gao, Jing, Zhang, Xiaotian, Li, Jian, Zhang, Cheng, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272556/
https://www.ncbi.nlm.nih.gov/pubmed/35811317
http://dx.doi.org/10.1186/s12916-022-02421-1