Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases

The RNA viruses SARS-CoV-2 and dengue pose a major threat to human health worldwide and their proteases (M(pro); NS2B/NS3) are considered as promising targets for drug development. We present the synthesis and biological evaluation of novel benzoxaborole inhibitors of these two proteases. The most a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kühl, Nikos, Lang, Johannes, Leuthold, Mila M., Klein, Christian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272583/
https://www.ncbi.nlm.nih.gov/pubmed/35863275
http://dx.doi.org/10.1016/j.ejmech.2022.114585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272583/
https://www.ncbi.nlm.nih.gov/pubmed/35863275
http://dx.doi.org/10.1016/j.ejmech.2022.114585

Ejemplares similares