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Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases

The RNA viruses SARS-CoV-2 and dengue pose a major threat to human health worldwide and their proteases (M(pro); NS2B/NS3) are considered as promising targets for drug development. We present the synthesis and biological evaluation of novel benzoxaborole inhibitors of these two proteases. The most a...

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Detalles Bibliográficos
Autores principales:	Kühl, Nikos, Lang, Johannes, Leuthold, Mila M., Klein, Christian D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Masson SAS. 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272583/ https://www.ncbi.nlm.nih.gov/pubmed/35863275 http://dx.doi.org/10.1016/j.ejmech.2022.114585

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