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Development of a Magnetic Nanostructure for Co-delivery of Metformin and Silibinin on Growth of Lung Cancer Cells: Possible Action Through Leptin Gene and its Receptor Regulation

OBJECTIVE: Chemotherapeutic combinational approaches would be more efficient in decreasing toxicity of drug, preventing tumor progression in relation to either drug alone. Hence, the aim of this study is to constract magnetic PLGA/PEG nanoparticles (NPs) co-loaded with Metformin (Met) and Silibinin...

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Detalles Bibliográficos
Autores principales: Salamni Javan, Elnaz, Lotfi, Fatemeh, Jafari-Gharabaghlou, Davoud, Mousazadeh, Hanieh, Dadashpour, Mehdi, Zarghami, Nosratollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272620/
https://www.ncbi.nlm.nih.gov/pubmed/35225464
http://dx.doi.org/10.31557/APJCP.2022.23.2.519