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Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD(+)-mediated mitonuclear communication through PGC1α/PPARγ signaling pathway
Endotoxin-induced acute lung injury (ALI) is a challenging life-threatening disease for which no specific therapy exists. Mitochondrial dysfunction is corroborated as hallmarks in sepsis which commonly disrupt mitochondria-centered cellular communication networks, especially mitonuclear crosstalk, w...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272656/ https://www.ncbi.nlm.nih.gov/pubmed/35816227 http://dx.doi.org/10.1007/s00011-022-01605-y |