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Cilia-Localized Counterregulatory Signals as Drivers of Renal Cystogenesis

Primary cilia play counterregulatory roles in cystogenesis—they inhibit cyst formation in the normal renal tubule but promote cyst growth when the function of polycystins is impaired. Key upstream cilia-specific signals and components involved in driving cystogenesis have remained elusive. Recent st...

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Detalles Bibliográficos
Autores principales: Walker, Rebecca V., Maranto, Anthony, Palicharla, Vivek Reddy, Hwang, Sun-Hee, Mukhopadhyay, Saikat, Qian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272769/
https://www.ncbi.nlm.nih.gov/pubmed/35832738
http://dx.doi.org/10.3389/fmolb.2022.936070