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Cilia-Localized Counterregulatory Signals as Drivers of Renal Cystogenesis
Primary cilia play counterregulatory roles in cystogenesis—they inhibit cyst formation in the normal renal tubule but promote cyst growth when the function of polycystins is impaired. Key upstream cilia-specific signals and components involved in driving cystogenesis have remained elusive. Recent st...
Autores principales: | Walker, Rebecca V., Maranto, Anthony, Palicharla, Vivek Reddy, Hwang, Sun-Hee, Mukhopadhyay, Saikat, Qian, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272769/ https://www.ncbi.nlm.nih.gov/pubmed/35832738 http://dx.doi.org/10.3389/fmolb.2022.936070 |
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