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Inhibin Inactivation in Female Mice Leads to Elevated FSH Levels, Ovarian Overstimulation, and Pregnancy Loss

Inhibins are members of the transforming growth factor-β family, composed of a common α-subunit disulfide-linked to 1 of 2 β-subunits (βA in inhibin A or βB in inhibin B). Gonadal-derived inhibin A and B act in an endocrine manner to suppress the synthesis of follicle-stimulating hormone (FSH) by pi...

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Detalles Bibliográficos
Autores principales: Walton, Kelly L, Goney, Monica P, Peppas, Zoe, Stringer, Jessica M, Winship, Amy, Hutt, Karla, Goodchild, Georgia, Maskey, Shreya, Chan, Karen L, Brûlé, Emilie, Bernard, Daniel J, Stocker, William A, Harrison, Craig A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272799/
https://www.ncbi.nlm.nih.gov/pubmed/35255139
http://dx.doi.org/10.1210/endocr/bqac025