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NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs

Multi-elemental, isotope selective nano-scale secondary ion mass spectrometry (NanoSIMS) combined with confocal laser-scanning microscopy was used to characterize the subcellular distribution of (15)N-labeled cisplatin in human colon cancer cells. These analyses indicated predominant cisplatin coloc...

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Detalles Bibliográficos
Autores principales: Legin, Anton A., Schintlmeister, Arno, Jakupec, Michael A., Galanski, Mathea S., Lichtscheidl, Irene, Wagner, Michael, Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273000/
https://www.ncbi.nlm.nih.gov/pubmed/35919909
http://dx.doi.org/10.1039/c3sc53426j