MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling

Obese women have a higher risk of developing endometrial cancer (EC) than lean women. Besides affecting EC progression, obesity also affects sensitivity of patients to treatment including medroxprogesterone acetate (MPA). Obese women have a lower response to MPA with an increased risk for tumor recu...

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Detalles Bibliográficos
Autores principales: Omar, Intan Sofia, Abd Jamil, Amira Hajirah, Mat Adenan, Noor Azmi, Chung, Ivy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273069/
https://www.ncbi.nlm.nih.gov/pubmed/35816477
http://dx.doi.org/10.1371/journal.pone.0270830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273069/
https://www.ncbi.nlm.nih.gov/pubmed/35816477
http://dx.doi.org/10.1371/journal.pone.0270830

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