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MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling
Obese women have a higher risk of developing endometrial cancer (EC) than lean women. Besides affecting EC progression, obesity also affects sensitivity of patients to treatment including medroxprogesterone acetate (MPA). Obese women have a lower response to MPA with an increased risk for tumor recu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273069/ https://www.ncbi.nlm.nih.gov/pubmed/35816477 http://dx.doi.org/10.1371/journal.pone.0270830 |