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Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

Recent studies demonstrate that immune checkpoint blockade (ICB) increases the chances of the abscopal effect, an anti-tumor effect outside the radiation field in radiation therapy. However, the optimal sequence between radiation and ICB remains unclear. To investigate the impact of sequence of radi...

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Detalles Bibliográficos
Autores principales: Katsuki, Shohei, Takahashi, Yutaka, Tamari, Keisuke, Minami, Kazumasa, Takenaka, Wataru, Ibuki, Yoriko, Yamamoto, Junya, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273087/
https://www.ncbi.nlm.nih.gov/pubmed/35816501
http://dx.doi.org/10.1371/journal.pone.0271205