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A protein–protein interaction map reveals that the Coxiella burnetii effector CirB inhibits host proteasome activity

Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which is featured by its ability to replicate in acid vacuoles resembling the lysosomal network. One key virulence determinant of C. burnetii is the Dot/Icm system that transfers more than 150 effector proteins into host cel...

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Detalles Bibliográficos
Autores principales: Fu, Mengjiao, Liu, Yuchen, Wang, Guannan, Wang, Peng, Zhang, Jianing, Chen, Chen, Zhao, Mingliang, Zhang, Shan, Jiao, Jun, Ouyang, Xuan, Yu, Yonghui, Wen, Bohai, He, Chengzhi, Wang, Jian, Zhou, Dongsheng, Xiong, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273094/
https://www.ncbi.nlm.nih.gov/pubmed/35816513
http://dx.doi.org/10.1371/journal.ppat.1010660