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A protein–protein interaction map reveals that the Coxiella burnetii effector CirB inhibits host proteasome activity
Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which is featured by its ability to replicate in acid vacuoles resembling the lysosomal network. One key virulence determinant of C. burnetii is the Dot/Icm system that transfers more than 150 effector proteins into host cel...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273094/ https://www.ncbi.nlm.nih.gov/pubmed/35816513 http://dx.doi.org/10.1371/journal.ppat.1010660 |