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Single-shot AAV-vectored vaccine against SARS-CoV-2 with fast and long-lasting immunity
Due to the insufficient long-term protection and significant efficacy reduction to new variants of current COVID-19 vaccines, the epidemic prevention and control are still challenging. Here, we employ a capsid and antigen structure engineering (CASE) strategy to manufacture an adeno-associated viral...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273293/ https://www.ncbi.nlm.nih.gov/pubmed/35846427 http://dx.doi.org/10.1016/j.apsb.2022.07.004 |