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Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features
Cancers of unknown primary (CUP) origin account for ∼3% of all cancer diagnoses, whereby the tumor tissue of origin (TOO) cannot be determined. Using a uniformly processed dataset encompassing 6756 whole-genome sequenced primary and metastatic tumors, we develop Cancer of Unknown Primary Location Re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273599/ https://www.ncbi.nlm.nih.gov/pubmed/35817764 http://dx.doi.org/10.1038/s41467-022-31666-w |