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Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice

Muscle disuse in the hindlimb unloaded (HU) mice causes significant atrophy and weakness. However, the cellular and molecular mechanisms driving disuse-muscle atrophy remain elusive. We investigated the potential contribution of proteins dysregulation by sarcoplasmic reticulum (SR), a condition call...

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Detalles Bibliográficos
Autores principales: Khan, Amir Ali, Gul, Muhammad Tehsil, Karim, Asima, Ranade, Anu, Azeem, Muhammad, Ibrahim, Zeinab, Ramachandran, Gopika, Nair, Vidhya A., Ahmad, Firdos, Elmoselhi, Adel, Qaisar, Rizwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273600/
https://www.ncbi.nlm.nih.gov/pubmed/35817772
http://dx.doi.org/10.1038/s41526-022-00211-w