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Transcriptional and post-transcriptional regulation of checkpoint genes on the tumour side of the immunological synapse

Cancer is a disease of the genome, therefore, its development has a clear Mendelian component, demonstrated by well-studied genes such as BRCA1 and BRCA2 in breast cancer risk. However, it is known that a single genetic variant is not enough for cancer to develop leading to the theory of multistage...

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Detalles Bibliográficos
Autores principales: Dobosz, Paula, Stempor, Przemysław A., Ramírez Moreno, Miguel, Bulgakova, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273643/
https://www.ncbi.nlm.nih.gov/pubmed/35459932
http://dx.doi.org/10.1038/s41437-022-00533-1