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A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss

Age-related hearing loss (ARHL) is the most common sensory impairment mainly caused by degeneration of sensory hair cells in the cochlea with no causal medical treatment available. Auditory function and sensory hair cell survival critically depend on the Kv7.4 (KCNQ4) channel, a voltage-gated potass...

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Detalles Bibliográficos
Autores principales: Peixoto Pinheiro, Barbara, Müller, Marcus, Bös, Michael, Guezguez, Jamil, Burnet, Michael, Tornincasa, Mara, Rizzetto, Riccardo, Rolland, Jean-Francois, Liberati, Chiara, Lohmer, Stefan, Adel, Youssef, Löwenheim, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273644/
https://www.ncbi.nlm.nih.gov/pubmed/35817766
http://dx.doi.org/10.1038/s41419-022-04915-5