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A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss
Age-related hearing loss (ARHL) is the most common sensory impairment mainly caused by degeneration of sensory hair cells in the cochlea with no causal medical treatment available. Auditory function and sensory hair cell survival critically depend on the Kv7.4 (KCNQ4) channel, a voltage-gated potass...
Autores principales: | Peixoto Pinheiro, Barbara, Müller, Marcus, Bös, Michael, Guezguez, Jamil, Burnet, Michael, Tornincasa, Mara, Rizzetto, Riccardo, Rolland, Jean-Francois, Liberati, Chiara, Lohmer, Stefan, Adel, Youssef, Löwenheim, Hubert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273644/ https://www.ncbi.nlm.nih.gov/pubmed/35817766 http://dx.doi.org/10.1038/s41419-022-04915-5 |
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