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Sulindac acetohydrazide derivative attenuates against cisplatin induced organ damage by modulation of antioxidant and inflammatory signaling pathways

This study aimed to explore the mechanisms of action of a sulindac acetohydrazide derivative, N'-(4-dimethylaminobenzylidene)-2-1-(4-(methylsulfinyl) benzylidene)-5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide, against anticancer drug cisplatin induced organ damage. Using a rodent model, vario...

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Detalles Bibliográficos
Autores principales: Razak, Suhail, Afsar, Tayyaba, Bibi, Nousheen, Abulmeaty, Mahmoud, Bhat, Mashooq Ahmad, Inam, Anam, Trembley, Janeen H., Almajwal, Ali, Shabbir, Maria, Alruwaili, Nawaf W., Algarni, Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273647/
https://www.ncbi.nlm.nih.gov/pubmed/35817806
http://dx.doi.org/10.1038/s41598-022-15950-9