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Sulindac acetohydrazide derivative attenuates against cisplatin induced organ damage by modulation of antioxidant and inflammatory signaling pathways
This study aimed to explore the mechanisms of action of a sulindac acetohydrazide derivative, N'-(4-dimethylaminobenzylidene)-2-1-(4-(methylsulfinyl) benzylidene)-5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide, against anticancer drug cisplatin induced organ damage. Using a rodent model, vario...
Autores principales: | Razak, Suhail, Afsar, Tayyaba, Bibi, Nousheen, Abulmeaty, Mahmoud, Bhat, Mashooq Ahmad, Inam, Anam, Trembley, Janeen H., Almajwal, Ali, Shabbir, Maria, Alruwaili, Nawaf W., Algarni, Abdulrahman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273647/ https://www.ncbi.nlm.nih.gov/pubmed/35817806 http://dx.doi.org/10.1038/s41598-022-15950-9 |
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