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JunB Is Critical for Survival of T Helper Cells

Clonal expansion and differentiation of various T helper subsets, such as Th1, Th2, and Th17 cells, depend on a complex of transcription factors, IRF4 and a BATF-containing AP-1 heterodimer. A major BATF heterodimeric partner, JunB, regulates Th17 differentiation, but the role of JunB in other T hel...

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Detalles Bibliográficos
Autores principales: Hsieh, Tsunghan, Sasaki, Daiki, Taira, Naoyuki, Chien, Hsiaochiao, Sarkar, Shukla, Seto, Yu, Miyagi, Mio, Ishikawa, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273772/
https://www.ncbi.nlm.nih.gov/pubmed/35837408
http://dx.doi.org/10.3389/fimmu.2022.901030