Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma

Exosome-mediated delivery of circular RNAs (circRNAs) is implicated in cancer progression. However, the role of exosomal circRNAs in the chemotherapy resistance of tumours remains poorly understood. Here we identified a novel circRNA, circWDR62. It was found that circWDR62 expression was upregulated...

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Detalles Bibliográficos
Autores principales: Geng, Xiuchao, Zhang, Yuhao, Lin, Xiaomeng, Zeng, Zhaomu, Hu, Jun, Hao, Liangchao, Xu, Jianglong, Wang, Xinjuan, Wang, Hong, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273787/
https://www.ncbi.nlm.nih.gov/pubmed/35817771
http://dx.doi.org/10.1038/s41419-022-05056-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273787/
https://www.ncbi.nlm.nih.gov/pubmed/35817771
http://dx.doi.org/10.1038/s41419-022-05056-5

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