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Deciphering the Intercellular Communication Between Immune Cells and Altered Vascular Smooth Muscle Cell Phenotypes in Aortic Aneurysm From Single-Cell Transcriptome Data

BACKGROUND: Vascular smooth muscle cell (VSMC) phenotype switching has been preliminarily found in aortic aneurysms. However, two major questions were raised: (1) What factors drive phenotypic switching of VSMCs in aortic aneurysms? (2) What role does VSMC phenotype transformation play in aortic ane...

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Detalles Bibliográficos
Autores principales: Cao, Genmao, Lu, Zhengchao, Gu, Ruiyuan, Xuan, Xuezhen, Zhang, Ruijing, Hu, Jie, Dong, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273830/
https://www.ncbi.nlm.nih.gov/pubmed/35837612
http://dx.doi.org/10.3389/fcvm.2022.936287