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Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with ill-defined pathogenesis, calling for urgent developments of new therapeutic regimens. Herein, we applied PandaOmics, an AI-driven target discovery platform, to analyze the expression profiles of central nervous system (C...

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Detalles Bibliográficos
Autores principales: Pun, Frank W., Liu, Bonnie Hei Man, Long, Xi, Leung, Hoi Wing, Leung, Geoffrey Ho Duen, Mewborne, Quinlan T., Gao, Junli, Shneyderman, Anastasia, Ozerov, Ivan V., Wang, Ju, Ren, Feng, Aliper, Alexander, Bischof, Evelyne, Izumchenko, Evgeny, Guan, Xiaoming, Zhang, Ke, Lu, Bai, Rothstein, Jeffrey D., Cudkowicz, Merit E., Zhavoronkov, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273868/
https://www.ncbi.nlm.nih.gov/pubmed/35837482
http://dx.doi.org/10.3389/fnagi.2022.914017