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Mediators of Obesity Do Not Influence SARS-CoV-2 Infection or Activation of Primary Human Lung Microvascular Endothelial Cells In Vitro

Clinical observations have shown that obesity is associated with the severe outcome of SARS-CoV-2 infection hallmarked by microvascular dysfunction in the lungs and other organs. Excess visceral fat and high systemic levels of adipose tissue (AT) derived mediators such as leptin and other adipokines...

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Detalles Bibliográficos
Autores principales: ter Ellen, Bram M., Niewold, Jelmer, Flikweert, Antine, Muller Kobold, Anneke C., Heeringa, Peter, van Meurs, Matijs, Smit, Jolanda M., van der Voort, Peter H. J., Rodenhuis-Zybert, Izabela A., Moser, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273911/
https://www.ncbi.nlm.nih.gov/pubmed/35837388
http://dx.doi.org/10.3389/fimmu.2022.879033