Development of a Multicellular 3D Tumor Model to Study Cellular Heterogeneity and Plasticity in NSCLC Tumor Microenvironment

Heterogeneity is a characteristic feature of solid tumors. Intra-tumor heterogeneity includes phenotypic diversity, epigenetic abnormalities, cell proliferation, and plasticity that eventually drives disease progression. Studying tumor heterogeneity in 2D culture is challenging as it cannot simulate...

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Detalles Bibliográficos
Autores principales: Arora, Leena, Kalia, Moyna, Dasgupta, Suman, Singh, Navneet, Verma, Anita K., Pal, Durba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273950/
https://www.ncbi.nlm.nih.gov/pubmed/35837091
http://dx.doi.org/10.3389/fonc.2022.881207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273950/
https://www.ncbi.nlm.nih.gov/pubmed/35837091
http://dx.doi.org/10.3389/fonc.2022.881207

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