Cargando…

Discovery of TCMs and derivatives against the main protease of SARS-CoV-2 via high throughput screening, ADMET analysis, and inhibition assay in vitro

The rapidly evolving Coronavirus Disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide with thousands of deaths and infected cases. For the identification of effective treatments against this disease, the main protease (M(pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Xinyu, Li, Binglin, Omarini, Alejandra B., Gand, Martin, Zhang, Xiaoli, Wang, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273959/
https://www.ncbi.nlm.nih.gov/pubmed/35846732
http://dx.doi.org/10.1016/j.molstruc.2022.133709