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SLAMF8 Downregulates Mouse Macrophage Microbicidal Mechanisms via PI3K Pathways

Signaling lymphocytic activation molecule family 8 (SLAMF8) is involved in the negative modulation of NADPH oxidase activation. However, the impact of SLAMF8 downregulation on macrophage functionality and the microbicide mechanism remains elusive. To study this in depth, we first analyzed NADPH oxid...

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Detalles Bibliográficos
Autores principales: Romero-Pinedo, Salvador, Barros, Domingo I. Rojas, Ruiz-Magaña, María José, Maganto-García, Elena, Moreno de Lara, Laura, Abadía-Molina, Francisco, Terhorst, Cox, Abadía-Molina, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273976/
https://www.ncbi.nlm.nih.gov/pubmed/35837407
http://dx.doi.org/10.3389/fimmu.2022.910112