Akt-Dependent Glycolysis-Driven Lipogenesis Supports Proliferation and Survival of Human Pulmonary Arterial Smooth Muscle Cells in Pulmonary Hypertension

Hyper-proliferation of pulmonary arterial vascular smooth muscle cells (PAVSMC) is an important pathological component of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). Lipogenesis is linked to numerous proliferative diseases, but its role in PAVSMC proliferation in PAH rema...

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Detalles Bibliográficos
Autores principales: Jiang, Lifeng, Goncharov, Dmitry A., Shen, Yuanjun, Lin, Derek, Chang, Baojun, Pena, Andressa, DeLisser, Horace, Goncharova, Elena A., Kudryashova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274086/
https://www.ncbi.nlm.nih.gov/pubmed/35836951
http://dx.doi.org/10.3389/fmed.2022.886868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274086/
https://www.ncbi.nlm.nih.gov/pubmed/35836951
http://dx.doi.org/10.3389/fmed.2022.886868

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