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NF-κB signaling controls H3K9me3 levels at intronic LINE-1 and hematopoietic stem cell genes in cis

Ionizing radiations (IR) alter hematopoietic stem cell (HSC) function on the long term, but the mechanisms underlying these effects are still poorly understood. We recently showed that IR induces the derepression of L1Md, the mouse young subfamilies of LINE-1/L1 retroelements. L1 contributes to gene...

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Detalles Bibliográficos
Autores principales: Pelinski, Yanis, Hidaoui, Donia, Stolz, Anne, Hermetet, François, Chelbi, Rabie, Diop, M’boyba Khadija, Chioukh, Amir M., Porteu, Françoise, Elvira-Matelot, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274146/
https://www.ncbi.nlm.nih.gov/pubmed/35802137
http://dx.doi.org/10.1084/jem.20211356