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NF-κB signaling controls H3K9me3 levels at intronic LINE-1 and hematopoietic stem cell genes in cis
Ionizing radiations (IR) alter hematopoietic stem cell (HSC) function on the long term, but the mechanisms underlying these effects are still poorly understood. We recently showed that IR induces the derepression of L1Md, the mouse young subfamilies of LINE-1/L1 retroelements. L1 contributes to gene...
Autores principales: | Pelinski, Yanis, Hidaoui, Donia, Stolz, Anne, Hermetet, François, Chelbi, Rabie, Diop, M’boyba Khadija, Chioukh, Amir M., Porteu, Françoise, Elvira-Matelot, Emilie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274146/ https://www.ncbi.nlm.nih.gov/pubmed/35802137 http://dx.doi.org/10.1084/jem.20211356 |
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