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Comparison of T790M Acquisition After Treatment With First- and Second-Generation Tyrosine-Kinase Inhibitors: A Systematic Review and Network Meta-Analysis

BACKGROUND: Lung adenocarcinoma is a common disease with a high mortality rate. Epidermal growth factor receptor (EGFR) mutations are found in adenocarcinomas, and oral EGFR-tyrosine kinase inhibitors (EGFR-TKIs) show good responses. EGFR-TKI therapy eventually results in resistance, with the most c...

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Detalles Bibliográficos
Autores principales: Hsieh, Po-Chun, Wu, Yao-Kuang, Huang, Chun-Yao, Yang, Mei-Chen, Kuo, Chan-Yen, Tzeng, I-Shiang, Lan, Chou-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274284/
https://www.ncbi.nlm.nih.gov/pubmed/35837103
http://dx.doi.org/10.3389/fonc.2022.869390