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Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling

Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from GM fermentation of dietary fiber serving as invisible mediators is yet unclear. Thus, the current study aimed to determin...

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Detalles Bibliográficos
Autores principales: Zuo, Kun, Fang, Chen, Liu, Zheng, Fu, Yuan, Liu, Ye, Liu, Lifeng, Wang, Yuxing, Yin, Xiandong, Liu, Xiaoqing, Li, Jing, Zhong, Jiuchang, Chen, Mulei, Xu, Li, Yang, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274492/
https://www.ncbi.nlm.nih.gov/pubmed/35844801
http://dx.doi.org/10.7150/ijbs.70644