Pioneering insights of extrachromosomal DNA (ecDNA) generation, action and its implications for cancer therapy

Extrachromosomal DNA (ecDNA) is a cancer-specific circular DNA molecule that is derived from chromosomes. In contrast with linear chromosomes, ecDNA exhibits a unique structure that can be representative of high chromosome accessibility, contributing to hyperactivated proto-oncogenes and malignant b...

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Detalles Bibliográficos
Autores principales: Li, Zesheng, Wang, Bo, Liang, Hao, Han, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274496/
https://www.ncbi.nlm.nih.gov/pubmed/35844796
http://dx.doi.org/10.7150/ijbs.73479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274496/
https://www.ncbi.nlm.nih.gov/pubmed/35844796
http://dx.doi.org/10.7150/ijbs.73479

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