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AKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease

Podocyte injury is involved in the onset and progression of diabetic kidney disease (DKD) and is associated with mitochondrial abnormalities. Defective mitochondrial DNA (mtDNA) replication results in mitochondrial dysfunction. However, whether podocyte mtDNA replication is impaired in DKD is still...

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Detalles Bibliográficos
Autores principales: Feng, Jun, Chen, Zhaowei, Ma, Yiqiong, Yang, Xueyan, Zhu, Zijing, Zhang, Zongwei, Hu, Jijia, Liang, Wei, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274505/
https://www.ncbi.nlm.nih.gov/pubmed/35844803
http://dx.doi.org/10.7150/ijbs.73493