Gallic acid induces T-helper-1-like T(reg) cells and strengthens immune checkpoint blockade efficacy

BACKGROUND: Foxp3(+) regulatory T (T(reg)) cells facilitate tumor immune evasion by forming a suppressive tumor microenvironment. Therefore, immune therapies promoting T(reg) fragility may greatly enhance immune checkpoint blockade (ICB) efficacy in cancers. METHODS: We have screened 2640 compounds...

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Detalles Bibliográficos
Autores principales: Deng, Biaolong, Yang, Biaolong, Chen, Jieqiong, Wang, Shuaiwei, Zhang, Weiqi, Guo, Yixian, Han, Yichao, Li, Hecheng, Dang, Yongjun, Yuan, Yaqin, Dai, Xueyu, Zang, Yuansheng, Li, Yangyang, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274539/
https://www.ncbi.nlm.nih.gov/pubmed/35817479
http://dx.doi.org/10.1136/jitc-2021-004037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274539/
https://www.ncbi.nlm.nih.gov/pubmed/35817479
http://dx.doi.org/10.1136/jitc-2021-004037

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