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Extrapolating evidence for molecularly targeted therapies from common to rare cancers: a scoping review of methodological guidance

OBJECTIVES: Cancer is increasingly classified according to biomarkers that drive tumour growth and therapies developed to target them. In rare biomarker-defined cancers, randomised controlled trials to adequately assess targeted therapies may be infeasible. Extrapolating existing evidence of targete...

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Detalles Bibliográficos
Autores principales: Cho, Doah, Cheyne, Saskia, Lord, Sarah J, Simes, John, Lee, Chee Khoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274540/
https://www.ncbi.nlm.nih.gov/pubmed/35820758
http://dx.doi.org/10.1136/bmjopen-2021-058350