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Extrapolating evidence for molecularly targeted therapies from common to rare cancers: a scoping review of methodological guidance
OBJECTIVES: Cancer is increasingly classified according to biomarkers that drive tumour growth and therapies developed to target them. In rare biomarker-defined cancers, randomised controlled trials to adequately assess targeted therapies may be infeasible. Extrapolating existing evidence of targete...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274540/ https://www.ncbi.nlm.nih.gov/pubmed/35820758 http://dx.doi.org/10.1136/bmjopen-2021-058350 |