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Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s

The Omicron variant of SARS-CoV-2 carries multiple unusual mutations, particularly in the receptor-binding domain (RBD) of the spike (S) protein. Moreover, host-adapting mutations, such as residues 493, 498, and 501, were also observed in the Omicron RBD, which indicates that it is necessary to eval...

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Detalles Bibliográficos
Autores principales: Li, Linjie, Han, Pu, Huang, Baihan, Xie, Yufeng, Li, Weiwei, Zhang, Di, Han, Pengcheng, Xu, Zepeng, Bai, Bin, Zhou, Jingya, Kang, Xinrui, Li, Xiaomei, Zheng, Anqi, Zhang, Rong, Qiao, Shitong, Zhao, Xin, Qi, Jianxun, Wang, Qihui, Liu, Kefang, Gao, George Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274624/
https://www.ncbi.nlm.nih.gov/pubmed/35821014
http://dx.doi.org/10.1038/s41421-022-00431-0