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Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s
The Omicron variant of SARS-CoV-2 carries multiple unusual mutations, particularly in the receptor-binding domain (RBD) of the spike (S) protein. Moreover, host-adapting mutations, such as residues 493, 498, and 501, were also observed in the Omicron RBD, which indicates that it is necessary to eval...
Autores principales: | Li, Linjie, Han, Pu, Huang, Baihan, Xie, Yufeng, Li, Weiwei, Zhang, Di, Han, Pengcheng, Xu, Zepeng, Bai, Bin, Zhou, Jingya, Kang, Xinrui, Li, Xiaomei, Zheng, Anqi, Zhang, Rong, Qiao, Shitong, Zhao, Xin, Qi, Jianxun, Wang, Qihui, Liu, Kefang, Gao, George Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274624/ https://www.ncbi.nlm.nih.gov/pubmed/35821014 http://dx.doi.org/10.1038/s41421-022-00431-0 |
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